| 150 | S Chanderpaul | West Indies v South Africa | 1998/99 | o1393 |
| 144 | T Bavuma | South Africa v West Indies | 2022/23 | o4540 |
| 128* | SD Hope | West Indies v South Africa | 2022/23 | o4540 |
| 120* | ND McKenzie | South Africa v Sri Lanka | 2000/01 | o1662 |
| 115* | GC Smith | South Africa v England | 2004/05 | o2224 |
| 108 | CL Hooper | West Indies v South Africa | 1998/99 | o1393 |
| 107 | Javed Miandad | Pakistan v South Africa | 1992/93 | o803 |
| 103* | MS Atapattu | Sri Lanka v Zimbabwe | 2002/03 | o1990 |
| 102* | KR Rutherford | New Zealand v Sri Lanka | 1994/95 | o965 |
| 100* | KP Pietersen | England v South Africa | 2004/05 | o2224 |