| 151 | Babar Azam | Pakistan v Nepal | 2023 | o4628 |
| 150 | MP Breetzke | South Africa v New Zealand | 2024/25 | o4829 |
| 133* | KS Williamson | New Zealand v South Africa | 2024/25 | o4829 |
| 127 | SD Hope | West Indies v Pakistan | 2022 | o4401 |
| 116 | Yasir Hameed | Pakistan v Bangladesh | 2003/04 | o2041 |
| 109* | Iftikhar Ahmed | Pakistan v Nepal | 2023 | o4628 |
| 108 | Shakib Al Hasan | Bangladesh v Pakistan | 2007/08 | o2702 |
| 107* | Abdul Razzaq | Pakistan v Zimbabwe | 2004/05 | o2183 |
| 106* | GD Phillips | New Zealand v Pakistan | 2024/25 | o4826 |
| 103 | Babar Azam | Pakistan v West Indies | 2022 | o4401 |
| 100* | MN Samuels | West Indies v Pakistan | 2006/07 | o2464 |