| 1 | 216 | HRC Came & LM Reece | Derbyshire v Middlesex | 2024 | a30993 |
| 2 | 286 | IS Anderson & A Hill | Derbyshire v Cornwall | 1986 | a4901 |
| 3 | 265 | ARG Thomas & OFM Sykes | Surrey v Derbyshire | 2025 | a31853 |
| 4 | 179 | DL Maddy & TR Ambrose | Warwickshire v Derbyshire | 2008 | a19158 |
| 5 | 158* | KJ Barnett & B Roberts | Derbyshire v Essex | 1984 | a4191 |
| 6 | 126* | CR Taylor & AG Botha | Derbyshire v Durham | 2006 | a17497 |
| 7 | 100 | RA Whiteley & ZJ Chappell | Derbyshire v Nottinghamshire | 2025 | a31804 |
| 8 | 94* | LD Sutton & JID Kerr | Derbyshire v Northamptonshire | 2002 | a14345 |
| 9 | 105 | DG Moir & RW Taylor | Derbyshire v Kent | 1984 | a4085 |
| 10 | 88 | AK Dal & S Conners | Derbyshire v Somerset | 2023 | a30168 |