| 6-15 | CEH Croft | West Indies v England | 1980/81 | o115 |
| 5-23 | FA Rose | West Indies v Pakistan | 1999/00 | o1588 |
| 4-16 | Tapash Baisya | Bangladesh v West Indies | 2004 | o2129 |
| 4-18 | Wasim Akram | Pakistan v West Indies | 1992/93 | o828 |
| 4-21 | DJ Bravo | West Indies v Zimbabwe | 2009/10 | o2974 |
| 4-24 | HR Bryan | West Indies v Australia | 1998/99 | o1433 |
| 4-26 | DJG Sammy | West Indies v Zimbabwe | 2009/10 | o2972 |
| 4-27 | SP Narine | West Indies v Australia | 2011/12 | o3264 |
| 4-29 | Abdul Razzaq | Pakistan v West Indies | 2004/05 | o2246 |
| 4-31 | NW Bracken | Australia v West Indies | 2008 | o2713 |
| 4-35 | TL Best | West Indies v Bangladesh | 2004 | o2128 |
| 4-49 | XJ Doherty | Australia v West Indies | 2011/12 | o3262 |
| 4-54 | CH Gayle | West Indies v New Zealand | 2002 | o1845 |
| 4-61 | OD Gibson | West Indies v India | 1996/97 | o1202 |