| 209 | BC Lara | West Indies v Sri Lanka | 2003 | t1648 |
| 180 | V Sehwag | India v West Indies | 2006 | t1806 |
| 148* | M Kaif | India v West Indies | 2006 | t1806 |
| 146 | RS Dravid | India v West Indies | 2006 | t1806 |
| 146 | KR Mayers | West Indies v Bangladesh | 2022 | t2468 |
| 141 | CH Gayle | West Indies v Bangladesh | 2004 | t1701 |
| 141* | Q de Kock | South Africa v West Indies | 2021 | t2424 |
| 122 | JE Root | England v West Indies | 2018/19 | t2346 |
| 120 | BC Lara | West Indies v India | 2006 | t1806 |
| 119* | LD Chandimal | Sri Lanka v West Indies | 2018 | t2308 |
| 118 | MS Atapattu | Sri Lanka v West Indies | 2003 | t1648 |
| 118 | R Ashwin | India v West Indies | 2016 | t2215 |
| 113 | WW Hinds | West Indies v Sri Lanka | 2003 | t1648 |
| 113 | Habibul Bashar | Bangladesh v West Indies | 2004 | t1701 |
| 111 | Mohammad Rafique | Bangladesh v West Indies | 2004 | t1701 |
| 104 | WP Saha | India v West Indies | 2016 | t2215 |
| 103* | Khaled Mashud | Bangladesh v West Indies | 2004 | t1701 |
| 102* | RL Chase | West Indies v England | 2018/19 | t2346 |
| 101* | S Chanderpaul | West Indies v Bangladesh | 2014 | t2139 |