| 152* | DL Haynes | West Indies v India | 1988/89 | a5982 |
| 151 | CB Lambert | Guyana v Barbados | 1997/98 | a10727 |
| 125* | XM Marshall | Jamaica v Guyana | 2004/05 | a16206 |
| 119 | S Chattergoon | Guyana v Barbados | 2005/06 | a16907 |
| 113* | RR Sarwan | Guyana v Leeward Islands | 2005/06 | a16897 |
| 112* | LMP Simmons | Trinidad and Tobago v Leeward Islands | 2008/09 | a19225 |
| 106* | GR Marsh | Australia v West Indies | 1990/91 | a6958 |
| 102* | S Chattergoon | Guyana v Antigua and Barbuda | 2001/02 | a13751 |
| 100* | EN Trotman | Barbados v Guyana | 1976/77 | a1838 |
| 100* | Javed Miandad | Pakistan v West Indies | 1987/88 | a5596 |
| 100 | CA Best | West Indies v England | 1989/90 | a6445 |