| 199 | D Elgar | South Africa v Bangladesh | 2017/18 | t2276 |
| 160 | G Kirsten | South Africa v Bangladesh | 2002/03 | t1621 |
| 139* | JH Kallis | South Africa v Bangladesh | 2002/03 | t1621 |
| 137 | HM Amla | South Africa v Bangladesh | 2017/18 | t2276 |
| 114 | HH Gibbs | South Africa v Bangladesh | 2002/03 | t1621 |