| 7-15 | GD McGrath | Australia v Namibia | 2002/03 | a14957 |
| 6-46 | EL Hawken | North West v Boland | 2021/22 | a28961 |
| 6-49 | MP Siboto | North West v KwaZulu-Natal | 2009/10 | a20405 |
| 5-24 | WA Deacon | Free State v North West | 2006/07 | a17745 |
| 5-27 | A Nel | Easterns v North West | 2000/01 | a13187 |
| 5-30 | E Leie | Lions v Knights | 2015/16 | a24318 |
| 5-32 | DJ Pryke | North West v England XI | 1999/00 | a12390 |
| 5-37 | SE Bond | New Zealanders v South Africa A | 2005/06 | a16908 |
| 5-38 | WA Deacon | Lions v Dolphins | 2008/09 | a19224 |
| 5-44 | MKDI Amerasinghe | Sri Lanka A v South Africa A | 2008/09 | a19169 |
| 5-44 | J Theron | South Africa v Zimbabwe | 2010/11 | a20820 |
| 5-44 | LL Tsotsobe | Lions v Warriors | 2014/15 | a23563 |
| 5-45 | JJ Pienaar | Easterns v North West | 2007/08 | a18454 |
| 5-47 | DS Matthews | North West v Western Province | 2017/18 | a25810 |
| 5-48 | MADI Hemantha | Sri Lanka A v South Africa A | 2024/25 | a31102 |
| 5-57 | H Janse van Rensburg | North West v Border | 2019/20 | a27721 |
| 5-75 | AF Erasmus | Easterns v North West | 2017/18 | a26197 |