| 176 | AB de Villiers | South Africa v Bangladesh | 2017/18 | a25772 |
| 166 | RE Levi | Cape Cobras v Titans | 2012/13 | a22223 |
| 162 | WJ Lubbe | Eastern Province v Boland | 2021/22 | a28999 |
| 157 | RD Rickelton | Lions v Cape Cobras | 2019/20 | a27966 |
| 147 | H Davids | Boland v North West | 2009/10 | a20498 |
| 146 | SR Tendulkar | India v Kenya | 2001/02 | a13773 |
| 135* | JG Strydom | Boland v Western Province | 2001/02 | a13912 |
| 134* | PJ van Biljon | Free State v Boland | 2014/15 | a23748 |
| 129* | HE van der Dussen | South Africa v India | 2021/22 | a28821 |
| 126 | I Gafieldien | Boland v KwaZulu-Natal Coastal | 2020/21 | a28249 |
| 125* | LD Ferreira | Boland v Border | 1996/97 | a10217 |
| 125 | JT Smuts | Eastern Province v Boland | 2021/22 | a28999 |
| 124 | PJ Malan | Cape Cobras v Lions | 2017/18 | a25924 |
| 123* | H Klaasen | South Africa v Australia | 2019/20 | a28011 |
| 122* | JL Ontong | Boland v South Western Districts | 2009/10 | a20289 |
| 119* | PJ van Biljon | Free State v Boland | 2016/17 | a24991 |
| 119 | H Olivier | Free State v Boland | 2018/19 | a27208 |
| 118* | JF Venter | Free State v Boland | 1999/00 | a12387 |
| 116 | H Davids | Cape Cobras v Lions | 2008/09 | a19382 |
| 116* | RR Hendricks | Knights v Cape Cobras | 2011/12 | a21594 |
| 115* | TG Mokoena | Easterns v Boland | 2015/16 | a24414 |
| 115* | KD Petersen | Boland v Western Province | 2016/17 | a24969 |
| 113 | WJ Smit | Boland v Free State | 2004/05 | a16507 |
| 112 | JP Kreusch | Warriors v Western Province Boland | 2004/05 | a16253 |
| 112 | HM Amla | South Africa v Sri Lanka | 2011/12 | a21696 |
| 112 | B Capell | KwaZulu-Natal Coastal v South Western Districts | 2020/21 | a28279 |
| 111 | SC Ganguly | India v Kenya | 2001/02 | a13773 |
| 111 | H Davids | Boland v South Western Districts | 2006/07 | a17894 |
| 111 | GL Cloete | Warriors v Cape Cobras | 2018/19 | a27004 |
| 110* | GA Edmeades | Boland v Easterns | 2015/16 | a24414 |
| 110 | T Bavuma | South Africa v India | 2021/22 | a28821 |
| 109 | Saim Ayub | Pakistan v South Africa | 2024/25 | a31306 |
| 108* | IJL Trott | Boland v North West | 2000/01 | a13042 |
| 108* | JM Henderson | North West v Boland | 2003/04 | a15579 |
| 108* | WJ Smit | Boland v Gauteng | 2005/06 | a17370 |
| 108 | AG Puttick | Cape Cobras v Warriors | 2013/14 | a22989 |
| 108 | SV Samson | India v South Africa | 2023/24 | a30641 |
| 107* | WR Landsdale | Gauteng v Boland | 2014/15 | a23970 |
| 107 | MN van Wyk | Dolphins v Cape Cobras | 2017/18 | a25897 |
| 106 | LJ Koen | Boland v Griqualand West | 2000/01 | a13205 |
| 106 | OA Ramela | Boland v Free State | 2010/11 | a21132 |
| 105 | L Brown | KwaZulu-Natal Inland v Boland | 2006/07 | a18045 |
| 104 | VC Drakes | Border v Boland | 1996/97 | a10217 |
| 104 | PJ Malan | Boland v Gauteng | 2021/22 | a28940 |
| 103* | I Gafieldien | Boland v KwaZulu-Natal Coastal | 2019/20 | a27995 |
| 103 | JN Malan | Boland v KwaZulu-Natal Coastal | 2022/23 | a29679 |
| 102* | G Kirsten | South Africa v Pakistan | 2002/03 | a14789 |
| 102 | EC Kriek | Boland v North West | 2011/12 | a21748 |
| 102 | MN Erlank | KwaZulu-Natal Coastal v Boland | 2020/21 | a28249 |
| 101 | ME Waugh | Australians v Boland | 1996/97 | a10357 |
| 101* | UKJ Birkenstock | Boland v North West | 2013/14 | a23071 |
| 101 | DG Bedingham | Boland v KwaZulu-Natal | 2017/18 | a26195 |
| 100* | JH Kallis | South Africa v Sri Lanka | 2000/01 | a13237 |
| 100 | SM Khomari | Boland v Northerns | 2017/18 | a26353 |
| 100 | AP Agathangelou | Easterns v Boland | 2019/20 | a27928 |