| 168* | Q de Kock | South Africa v Bangladesh | 2017/18 | o3923 |
| 145* | KS Williamson | New Zealand v South Africa | 2012/13 | o3325 |
| 131 | JC Buttler | England v South Africa | 2022/23 | o4514 |
| 119 | CH Gayle | West Indies v Kenya | 2002/03 | o1980 |
| 118 | DJ Malan | England v South Africa | 2022/23 | o4514 |
| 116* | Inzamam-ul-Haq | Pakistan v Sri Lanka | 1997/98 | o1309 |
| 110* | Mushfiqur Rahim | Bangladesh v South Africa | 2017/18 | o3923 |
| 110* | HM Amla | South Africa v Bangladesh | 2017/18 | o3923 |
| 108* | HH Gibbs | South Africa v Sri Lanka | 2002/03 | o1911 |
| 101 | G Kirsten | South Africa v New Zealand | 2000/01 | o1651 |