| 122 | Babar Azam | Pakistan v South Africa | 2020/21 | itt1147 |
| 118 | J Charles | West Indies v South Africa | 2022/23 | itt2033 |
| 117 | RR Hendricks | South Africa v Pakistan | 2024/25 | itt3044 |
| 107* | NT Tilak Varma | India v South Africa | 2024/25 | itt2947 |
| 100 | Q de Kock | South Africa v West Indies | 2022/23 | itt2033 |