| 113 | RD Rickelton | MI Cape Town v Durban's Super Giants | 2025/26 | tt16245 |
| 112* | H Davids | Cape Cobras v Warriors | 2008/09 | tt1068 |
| 106* | JG Hermann | Sunrisers Eastern Cape v MI Cape Town | 2023/24 | tt13098 |
| 106 | MA Lagadien | South Africa High Performance XI v Western Province | 2026/27 | tt17456 |
| 105 | EM Moore | Western Province v Northerns | 2025/26 | tt15924 |
| 103* | D Smith | Western Province v Gauteng | 2025/26 | tt15972 |
| 101 | EM Moore | Western Province v KwaZulu-Natal Inland | 2023/24 | tt13423 |
| 101 | DT Brevis | Pretoria Capitals v Sunrisers Eastern Cape | 2025/26 | tt16398 |
| 100* | K Zondo | Impi v Cape Cobras | 2011/12 | tt2691 |